OK, I'll stick with the italian seasoned bread crumbs, although the place in Pittsburgh uses the Panko Bread Crumbs in their meatballs, they said it doesn't overwhelm the meatball.
I'm certain it doesn't -- But I suspect its because of how Panko is made.
The bread is 'baked' via electrocution.
So, it comes out light, airy, and entirely without a crust. Which is why its good for frying, because it gets that crust its lacking then. Baking with Panko is like baking with little balls of dried dough, which I suppose is exactly what Panko is.