Tennessee once had a U.S. Senator, William Brock (R), who served 1971-1977, but lost in 1976. I dunno why he lost re-election, as he seemed a pretty good guy.
Some years later, Brock ran for the U.S. Senate from Maryland, and lost big time.
James Buckley (C) was a U.S. Senator from New York, who served 1970-1977, but lost in 1976, to Daniel Monihan (D).
Some years later, Buckley ran for the U.S. Senate from Connectict, and lost.
Just some history trivia while I'm being inundated with snow out here.