Hitlery has a certain edge with the vagina-voters (I.e., women who will always vote for the woman on the ticket, no matter how awful she is in comparison to the other candidate, just because of the vagina). However, an old silver-spoon White woman with chronic honesty problems, a stiff verbal delivery only marginally better than Jeb's, and no redeeming social graces is a tough sell with Blacks, Latinos, and Millennials.
For her to lose, it's not necessary that those groups actually defect to Trump or the GOP nominee, it's only necessary that they don't bother to show up at the polls.