Just want to clarify for frank that these aren't "medicine" per se, they're basically a supplement with high amounts of Vitamin C and some Minerals. What you basically do is take them at the 1st sign of not feeling well, you can take them 2-3 times a day for a couple of days. My Husband and I believe in Conventional Medicine, but we've been using this for a few years and knock wood we haven't had a cold at all, just minor symptoms, we swear by this stuff.